ついに再手術を決心したコリンは、手術の前日、エイミーとブライトを誘い出して、思い出作りの1日を送ろうとする。死ぬことを前提としているかのようなコリンの行動にエイミーは腹を立て、必ず戻ってくることをコリンに約束させる。Dr.ブラウンは、子供たちを連れて恩師のDr.ドナルド・ダグラスを訪ねた。以前は難しいオペを前にしたとき、必ずドナルドの教えを請うていたのだ。ドナルドはもし手術が失敗したとき、ブラウンがつらい思いをすることを心配して、手術はやめるよう忠告する。
（シーズン1最終回）
ゲスト：フィリップ・ベイカー・ホール「マグノリア」、ナンシー・エバーハード（トム・アマンデスの実妻）
脚本：マイケル・グリーン、リーナ・ミモーン ［ストーリー：グレッグ・バーランティ、ヴァネッサ・テイラー］
監督：サンディ・スモラン
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