ガルシアのシステムがレプリケーターによる侵入を受けた。合成麻薬事件が一件落着し、一旦解散したBAUメンバーにホッチが深夜の招集をかけるが、ストラウスだけ連絡がつかない。ロッシがホテルの部屋に駆けつけるとストラウスの姿はなく、床にはミニバーのボトルが散乱していた……。
「人が苦痛を感じるのは、憂うためではなく目覚めるため。悔やむためではなく賢くなるため」
H・G・ウェルズ (イギリスの著作家)
「本当の家族を結ぶ絆は血ではない。互いの人生を尊び、喜ぶ心だ」
リチャード・バック (アメリカの飛行家、作家)
ゲスト：マーク・ハミル『スター・ウォーズ』
脚本：エリカ・メッサー
監督：グレン・カーショウ
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